Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®770 is a near-infrared fluorescent dye (Ex/Em 770/797 nm) with exceptional brightness for in vivo imaging or near-IR western blotting.
Type: Primary
Antigen: PODXL
Clonality: Monoclonal
Clone: Clone 2A4
Conjugation: CF770
Epitope:
Host: Mouse
Isotype: IgM
Reactivity: Human, Rabbit, Rat