Anti-CD79A Mouse Monoclonal Antibody (Biotin) [clone: JCB117]

Supplier: Biotium

BNCB0476-500 BNCB0476-100
75907-664EA 547.44 USD
75907-664 75907-662
Anti-CD79A Mouse Monoclonal Antibody (Biotin) [clone: JCB117]
Antibodies
CD79 is a disulfide-linked heterodimer of mb-1 (or CD79a) and B29 (or CD79b) polypeptidesIt is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

Type: Primary
Antigen: CD79A
Clonality: Monoclonal
Clone: Clone JCB117
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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