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Anti-CD74 Mouse Monoclonal Antibody (CF405M) [clone: Clone LN-2]

Supplier: Biotium
BNC050056-500 BNC050056-100
This antibody recognizes a protein of ~35 kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405M is a blue fluorescent dye (Ex/Em 408/452 nm) with superior brightness and photostability compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CD74
Clonality: Monoclonal
Clone: Clone LN-2
Conjugation: CF405M
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Baboon, Human, Mouse




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 μL BNC050056-100 75910-590 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

500 μL BNC050056-500 75910-592 Each (500µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol CD74
Antigen Name CD74
Reactivity Human, Mouse, Baboon Baboon, Human, Mouse
Conjugation CF™ 405M
Clonality Monoclonal
Antibody Type Primary
Clone LN-2
Host Mouse
Isotype IgG1, kappa
ImmunoChemistry Yes
ImmunoFluorescence Yes
Gene ID Unigene ID: 436568
Concentration 0.1 mg/mL
Storage Buffer PBS/0.1% BSA/0.05% azide
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