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Anti-TG Mouse Monoclonal Antibody (CF568) [clone: Clone 6E1.]

Supplier: Biotium
BNC680051-500 BNC680051-100
Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Type: Primary
Antigen: TG
Clonality: Monoclonal
Clone: Clone 6E1.
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 μL BNC680051-100 75975-096 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

500 μL BNC680051-500 75975-098 Each (500µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol TG
Antigen Name Thyroglobulin
Reactivity Human
Conjugation CF™ 568
Clonality Monoclonal
Antibody Type Primary
Clone 6E1.
Host Mouse
Isotype IgG1, kappa
ImmunoChemistry Yes
ImmunoFluorescence Yes
Gene ID Unigene ID: 654591
Concentration 0.1 mg/mL
Storage Buffer PBS/0.1% BSA/0.05% azide
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