Anti-Ilk Rabbit Polyclonal Antibody

Supplier: BioVision
3423-30T
76209-064EA 103.91 USD
76209-064
Anti-Ilk Rabbit Polyclonal Antibody
ILKs (Integrin-linked kinases) in combination with integrins and growth factors regulate cell survival, cell cycle, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extra-cellular matrix (ECM) and growth factor receptors to the actin cytoskeleton throμgh interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin. ILK phosphorylates several cellular targets including Akt, GSK-3, myosin light chain 2, as well as affixin. These phosphorylation events are key regulatory steps in modulating the activities of the targets.

Type: Primary
Antigen: Ilk
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit IgG
Reactivity: Human;Mouse;Rat
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