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Anti-AMACR Mouse Monoclonal Antibody [clone: AMACR/1723]

Supplier: BioVision
A1428-100
This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

IF: 1-2 ug/ml, IHC: 1-2 ug/ml

Type: Primary
Antigen: AMACR
Clonality: Monoclonal
Clone: AMACR/1723
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: Mouse IgG
Reactivity: Human




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg A1428-100 76199-264 Each (100µG) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol AMACR
Antigen Name Alpha-methylacyl-CoA racemase
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone AMACR/1723
Host Mouse
Isotype Mouse IgG
ImmunoChemistry Yes
Gene ID 23600
Immunogen Recombinant human full-length AMACR protein
Purification Protein A/G purification
Form Liquid
Storage Temperature -20°C
Shipping Temperature gel pack
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