Clioquinol ≥97%
Synonyms:
5-Chloro-8-hydroxy-7-iodoquinoline
, Clioquinol
, 5-Chloro-7-iodo-8-quinolinol
Metalloproteinase activator.
A metal chelating ligand which displays protective effects in various neurodegenerative states. It has shown to modulate amyloid β-peptide accumulation via upregulation of metalloprotease activity. When co-administered with vitamin B12 it totally rescues lead-induced impairments of synaptic plasticity in an animal model.
Formula:
C₉H₅ClINO MW: 305.5 g/mol |
MDL Number:
MFCD00006787 CAS Number: 130-26-7 |
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