Dimebon dihydrochloride ≥98% (by TLC)
Antihistamine with cognition-enhancing properties
Antihistamine that possesses cognition-enhancing properties. Blocks mitochondrial permeability transition pore opening induced by MPP+ and β-amyloid. Has been shown to interact with a number of molecular targets including acetylcholinesterases, NMDA receptors and L-type calcium channels as well as acting as an antagonist at 5-HT6 receptors. Dimebon significantly improved the clinical course of patients with mild-to-moderate Alzheimer’s disease in a randomized, double-blind, placebo-controlled study.
Formula:
C₂₁H₂₅N₃·2HCl MW: 319.4 · 73.0 g/mol |
CAS Number:
97657-92-6 |
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