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Supplier: Enzo Life Sciences
Synonyms: L-2-Amino-5-ureidopentanamide

Selective inhibitor of GABA and glycine uptake

FrPbAII is a component of the Parawixia bistriata spider venom. It has been shown to be a selective inhibitor of GABA and glycine uptake (IC50=65µM and 62µM respectively) with little or no effect on monoamine or glutamate transporters. It produces neuroprotective effects in a rat retinal ischemia/reperfusion model displaying remarkable reduction in cell death. It also abolishes convulsive tonic-clonic seizures induced by bicuculline (Prod. No. BML-EA149) in rats. Active in vivo. Crosses the blood-retina barrier.

Formula: C₆H₁₄N₄O₂
MW: 174,20 g/mol
CAS Number: 214975-80-1



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Size Supplier No. VWR Catalog Number Unit Price Quantity
5 mg BML-EA150-0005 89157-520 Each Retrieving Restricted

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Molecular Weight 210.7
Purity ≥98% (NMR)
Chemical Formula C6H14N4O2 . HCl
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