D-(-)-Penicillamine ≥99%, white powder

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
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Synonyms: H-D-Pen-OH(S)-2-Amino-3-mercapto-3-methylbutanoic acid

0215180501 0215180505 0215180525
76102-726EA 51.35 USD
76102-726 76102-728 76102-730
D-(-)-Penicillamine ≥99%, white powder
D(-)-Penicillamine

Physiological chelating agent for heavy metals.
It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.
Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity.
+4°C


  • Presentation: White Powder
  • H2O: soluble (100 mg/mL)

Formula: C₅H₁₁NO₂S
MW: 149.2 g/mol
Melting Pt: 210 °C (dec., lit.)
Storage Temperature: Refrigerator
MDL Number: MFCD00064302
CAS Number: 52-67-5

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Specification Test Results

Identity Test Passes
Purity ≥99%
FTIR Conforms to Standard

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