Protamine sulfate (from salmon sperm), ≥100 USP u/mg, white powder cell culture reagent

Supplier: MP BIOMEDICALS (FKA ICN BIOMED

Synonyms: Salmine sulphateSalmine sulfate

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76177-886EA 89.91 USD
76177-886 76177-884 76177-888 76177-892 76177-890
Protamine sulfate (from salmon sperm), ≥100 USP u/mg, white powder cell culture reagent
Protamine sulfate

Storage: Room Temperature, desiccate
Protamine sulfate is a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish, which has the property of neutralizing heparin. Because of having many basic amino acids (mostly arginine) protamine contains far greater nitrogen than other proteins. Its molecular weight is relatively small. Histone and other basic proteins in the testes of unmatured fishes convert into protamine along with the growth of the fishes. In the testes, protamine takes the form of nucleoprotamine linked with DNA.
Protamine Sulfate is a raw material for study preparations like insulin compounds, and etc. It is used in separation and refining of vaccines. It is a reagent for removing nucleic acids from enzyme solution for the purpose of easy separation and refining. Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Inhibits lipoprotein lipase. Protamine sulfate shown to inhibit the classical pathway of complement. It inhibits turnover of lipoproteins by lipoprotein lipase.


  • Cell Culture Reagent Grade
  • Presentation: White Powder
  • Freely soluble in hot water, slightly soluble in cold water; soluble in 0.1 M KH2PO4; Soluble in HCl. Practically insoluble in organic solvents.

Storage Temperature: Ambient
MDL Number: MFCD00132091
CAS Number: 9009-65-8

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Specification Test Results

Identity Test Passes
Source Salmon Sperm
Loss on Drying ≤5%
Sulfate 16-22%
Nitrogen 22.5-25.5%
Activity ≥100 USP u/mg

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