Tenovin-1
Synonyms:
N-((4-Acetamidophenyl)carbamothioyl)-4-(tert-butyl)benzamide
9400-25
9400-5
76021-932EA
99.24
USD
76021-932
76021-934
Tenovin-1
Tenovin-1
Tenovin-1 is a small molecule p53 activator that protects against MDM2-mediated p53 degradation
It acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro.
Formula:
C₂₀H₂₃N₃O₂S MW: 369,48 g/mol |
MDL Number:
MFCD02914760 CAS Number: 380315-80-0 |
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