Tenovin-1

Synonyms: N-((4-Acetamidophenyl)carbamothioyl)-4-(tert-butyl)benzamide

9400-25 9400-5
76021-932EA 99.24 USD
76021-932 76021-934
Tenovin-1
Tenovin-1

Tenovin-1 is a small molecule p53 activator that protects against MDM2-mediated p53 degradation


 It acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro.

Formula: C₂₀H₂₃N₃O₂S
MW: 369,48 g/mol
MDL Number: MFCD02914760
CAS Number: 380315-80-0
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