RG7388
Supplier: BioVision
Synonyms:
4-((2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid
RG7388 is highly a potent and selective inhibitor of p53-MDM2 interaction
RG7388 blocks p53−MDM2 binding and effectively activates the p53 pathway, leading to cell cycle arrest and/or apoptosis in cell lines expressing wild-type p53 and tumor growth inhibition or regression of osteosarcoma xenografts in nude mice.
Formula:
C₃₁H₂₉Cl₂F₂N₃O₄ MW: 616,48 g/mol |
MDL Number:
MFCD26142931 CAS Number: 1229705-06-9 |
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