GDC-0449, EZSolution™

Synonyms: 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulphonyl)benzamideVismodegib2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide

2539-5
76020-922EA 157.61 USD
76020-922
GDC-0449, EZSolution™
GDC-0449

A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway


Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.

Formula: C₁₉H₁₄Cl₂N₂O₃S
MW: 421.3 g/mol
MDL Number: MFCD12407408
CAS Number: 879085-55-9
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