Hypericin

Danger

2526-1 2526-5
76020-834EA 391.11 USD
76020-834 76020-832
Hypericin
Hypericin

Isolated from Hypericum perforatum, St. John’s Wort. Hypericin has been shown to display antiviral and antiretroviral activity. A potent and selective inhibitor of protein kinase C (IC₅₀ = 3.4 µM). Also known to inhibit Casein Kinase II (CKII), MAP Kinase, Insulin R, EGFR, PI-3 Kinase. Displays antineoplastic and antitumor actitities. Most activities require light activation. Induces apoptosis in neuroblastoma cells at 1 µM or above (IC₅₀ = 0.1 µM at 29 mW/cm2 (tungsten light)). Used in photodynamic treatment of tumors and has been reported to be cytotoxic to some tumor cell lines when Hypericin is photoactivated.


Storage Temperature: -20°C

Formula: C₃₀H₁₆O₈
MDL Number: MFCD00016683
CAS Number: 548-04-9
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