PF-03394197
Synonyms:
N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide
, N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulphonamide
PF-03394197 is potent and selective Janus kinase (JAK) inhibitor
It inhibits JAK family members with an IC₅₀ of 10-99 nM being most potent against JAK1 (IC₅₀ = 10 nM). PF-03394197 does not inhibit a panel of 38 non-JAK kinases (IC₅₀ >1 µM). Displays activity against cytokines involved in allergy.
Formula:
C₁₅H₂₃N₅O₂S MW: 337,44 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD25976611 CAS Number: 1208319-26-9 |
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