WHI-P154 ≥98% (by HPLC)
Synonyms:
2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol
, 2-Bromo-4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol
2659-5
2659-25
76021-396EA
87.57
USD
76021-396
76021-398
WHI-P154 ≥98% (by HPLC)
WHI-P154
WHI-P154 is a potent JAK3 inhibitor (IC₅₀ of 1.8 μM). It displays no activity against JAK1 or JAK2. Also inhibits EGFR, Src, Abl, VEGFR and MAPK, and prevents Stat3, but not Stat5 phosphorylation. Induces differentiation of neural progenitor cells
- Appearance: White to off-white solid
Formula:
C₁₆H₁₄BrN₃O₃ MW: 376.2 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD02179366 CAS Number: 211555-04-3 |
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