XL888

Synonyms: 5-(((R)-sec-Butyl)amino)-N1-((3-endo)-8-(5-(cyclopropanecarbonyl)pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methylterephthalamide

2654-5 2654-1
76021-376EA 110.74 USD
76021-376 76021-378
XL888
XL888

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity


XL888 specifically binds to Hsp90, inhibiting its chaperone function and promoting the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

Formula: C₂₉H₃₇N₅O₃
MW: 503,64 g/mol
Storage Temperature: Freezer
MDL Number: MFCD22124888
CAS Number: 1149705-71-4
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