Bromosporine ≥98% (by HPLC)
Synonyms:
Ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate
, Ethyl (3-methyl-6-(4-methyl-3-(methylsulphonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate
2652-5
2652-1
76021-368EA
87.57
USD
76021-368
76021-370
Bromosporine ≥98% (by HPLC)
Bromosporine
Bromosporine is a broad spectrum bromodomain inhibitor (IC₅₀s = 0.41 µM, 0.29 µM, 0.122 µM and 0.017 µM for BRD2, BRD4, BRD9 and CECR2, respectively). At 1 µM, Bromosporine accelerates FRAP recovery of BRD4 and CREBBP, while displaying no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 µM.
Formula:
C₁₇H₂₀N₆O₄S MW: 404.44 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD26142669 CAS Number: 1619994-69-2 |
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