γ-Secretase inhibitor XX ≥98% (by HPLC)

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Synonyms: (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide

2649-5 2649-1
76021-358EA 344.42 USD
76021-358 76021-356
γ-Secretase inhibitor XX ≥98% (by HPLC)
gamma-Secretase inhibitor XX

DBZ is a potent γ-secretase inhibitor that blocks the cleavage of Notch into its active signaling effector, Notch intracellular domain, in human T cell lymphoma (SupT1) cells (IC₅₀ = 1.7 nM).

Formula: C₂₆H₂₃F₂N₃O₃
MW: 463.48 g/mol
Storage Temperature: Freezer
MDL Number: MFCD12828734
CAS Number: 209984-56-5
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Specification Test Results

Purity ≥98% (HPLC)
Appearance White to Off-White Solid

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