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IPA-3, Biovision Inc

Supplier: BioVision
IPA-3 is a cell-permeable allosteric inhibitor of PAK1 (tha p21-activated kinase 1) that is non-competitive with respect to ATP binding (IC₅₀ = 2.5 µM). It does not, however, inhibit the activity of PAK1 that has been pre-activated with Cdc42. IPA-3 binds covalently to the PAK1 regulatory domain (apparent Kd = 1.9 uM) and prevents binding to the upstream activator Cdc42. Potential anti-tumor agent.

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Size Storage Temperature Package Supplier No. VWR Catalog Number Unit Price Quantity
25 mg -20°C Plastic vials 2647-25 76021-350 Each (25mg) Retrieving Restricted
5 mg -20°C Plastic vials 2647-5 76021-348 Each (5mg) Retrieving Restricted
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CAS No. 42521-82-4
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