ACY-1215 ≥98% (by HPLC)

Synonyms: 2-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamideACT-1215Rocilinostat

2629-5 2629-25
76021-286EA 99.24 USD
76021-286 76021-288
ACY-1215 ≥98% (by HPLC)
ACY-1215

ACY-1215 is a potent, cell-permeable and selective inhibitor of histone deacetylase 6 (HDAC6) (IC₅₀ = 5 nM). ACY-1215 is 12-, 10-, 11 and 21-fold less active against HDAC1, HDAC2, HDAC3 and HDAC8, respectively. It displays minimal activities (IC₅₀ > 1 µM) against HDAC4, HDAC5, HDAC7, HDAC9, HDAC11, Sirtuin1, and Sirtuin2. In combination with Tubastatin (Cat. No. 1724), it improves cognition in Alzheimer’s Disease (AD) transgenic mice.


  • Appearance: White to off-white solid

Formula: C₂₄H₂₇N₅O₃
MW: 433.50 g/mol
Storage Temperature: Freezer
MDL Number: MFCD22666356
CAS Number: 1316214-52-4
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