Myriocin
Synonyms:
ISP-1
2567-5
2567-25
76021-016EA
122.58
USD
76021-016
76021-018
Myriocin
Myriocin
A fungal metabolite with potent immunosuppressant activity that is 10-100 fold more compared to Cyclosporin A (Cat
No. 1522). It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide. It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.
Storage Temperature:
Freezer |
MDL Number:
MFCD01632772 CAS Number: 35891-70-4 |
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