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Anti-PPP1R14A Mouse Monoclonal Antibody [clone: 4H10]

PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.

WB: 1:500-1:1,000

Type: Primary
Antigen: PPP1R14A
Clonality: Monoclonal
Clone: 4H10
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µl 10R-1093 101978-686 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol PPP1R14A
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone 4H10
Host Mouse
Isotype IgG2a kappa
Western Blot Yes
Concentration 1 mg/ml
Format Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Immunogen PPP1R14A antibody was raised in mouse using recombinant human PPP1R14A (1-147aa) purified from E. coli as the immunogen.
Storage Temperature Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
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