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Anti-PP2CA Mouse Monoclonal Antibody [clone: p6c7]

This antibody was derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant p6c7.Protein phosphatase 2C(PP2Calpha) is a Mn+/- or Mg +/-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNk MAPk pathways and regulates cellular stress response in eukaryotes. The PPM(metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2Calpha, the prototypical member of the PPM family.

WB: 1:250-1:500

Type: Primary
Antigen: PP2CA
Clonality: Monoclonal
Clone: p6c7
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µl 10R-1005 101978-512 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol PP2CA
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone p6c7
Host Mouse
Isotype IgG2b kappa
Western Blot Yes
ImmunoPrecipitation Yes
Concentration 1 mg/ml
Format Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Immunogen PP2Calpha antibody was raised in mouse using recombinant human PP2Calpha (1-382aa) purified from E. coli as the immunogen.
Storage Temperature Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping Temperature *Blue Ice*
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