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Anti-PAX6 Mouse Monoclonal Antibody [clone: 1C8]

Supplier: FITZGERALD INDUSTRIES INTNL MS
10R-2205
PAX6 is the most researched of the PAX genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription.

ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:500-1:2000

Type: Primary
Antigen: PAX6
Clonality: Monoclonal
Clone: 1C8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity:




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µl 10R-2205 101980-736 Each (1ml) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol PAX6
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone 1C8
Host Mouse
Isotype IgG1
Western Blot Yes
ELISA Yes
ImmunoFluorescence Yes
Concentration 1.0 mg/ml
Format Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Immunogen PAX6 antibody was raised in Mouse using a purified recombinant fragment of human PAX6 expressed in E. coli as the immunogen.
Storage Temperature Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping Temperature *Blue Ice*
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