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Anti-PAX6 Mouse Monoclonal Antibody [clone: 1C8]

Supplier: Fitzgerald Industries

10R-2205

101980-736EA 786.46 USD

101980-736

Anti-PAX6 Mouse Monoclonal Antibody [clone: 1C8]

Antibodies

PAX6 is the most researched of the PAX genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription.

ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:500-1:2000

Type: Primary
Antigen: PAX6
Clonality: Monoclonal
Clone: 1C8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity:

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