Doxorubicin hydrochloride ≥95%

Supplier: MP BIOMEDICALS (FKA ICN BIOMED

Synonyms: (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochlorideHydroxydaunorubicin Hydrochloride

0215910101 0215910105
IC0215910105EA 225.01 USD
IC0215910105 IC0215910101
Doxorubicin hydrochloride ≥95%
Doxorubicin hydrochloride

Doxorubicin hydrochloride blocks RNA polymerase and reverse transcriptase. It also inhibits nucleic acid synthesis and induces apoptosis.


  • Inhibits nucleic Acid synthesis
  • Induces apoptosis
  • Substrate of MRP1


Naturally fluorescent anthracycline antibiotic, anticancer drug


Doxorubicin Hydrochloride is a chemotherapeutic, antitumor, immunosuppressive, and antibiotic agent.


Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. The fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.


Reddish orange powder


Soluble in water (>10 mg/mL), in isotonic sodium chloride, methanol, aqueous alcohols, DMSO (> 10 mg/mL); practically insoluble in chloroform, ether, and other organic solvents.

Formula: C₂₇H₂₉NO₁₁·HCl
MW: 579.98 g/mol
Melting Pt: 216 °C (dec., lit.)
Storage Temperature: Ambient
MDL Number: MFCD00077757
CAS Number: 25316-40-9
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