Human Recombinant Irisin (active) (from E. coli)

Supplier: BioVision
AB285980-10UG AB285980-50UG
75837-984EA 750.79 USD
75837-984 75837-986
Human Recombinant Irisin (active) (from E. coli)
Proteins and Peptides
Irisin is a recently discovered exercise-induced myokine, which is secreted by skeletal muscles and produced by cleavage of the FNDC5. Studies show that Irisin stimulates mitochondria uncoupling protein-1 (UCP-1; a regulator of thermogenic capability of brown fat) expression, so Irisin can upregulate white to brown fat conversion and improve systemic metabolism by increasing energy expenditure. Hence, Irisin is a potential new drug target in the study of metabolic disorders, such as obesity and type 2 diabetes mellitus (T2DM). Moreover, FNDC5-like receptors are conserved in vertebrates and critical for neuronal development.
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