BML-286 ≥98% (by HPLC)
Supplier: Enzo Life Sciences
BML-WN113-0010
76002-428EA
128.48
USD
76002-428
BML-286 ≥98% (by HPLC)
BML-286
Disrupts Wnt signaling
Cell-permeable compound that disrupts Wnt signaling by binding to the PDZ domain of dishevelled (Kd=10.6 µM). Blocked Wnt3a-induced transcription activity and was able to supress the Wnt pathway-dependent growth of prostate cancer PC-3 cells (IC50=12.5 µM). BML-286 was also capable of supressing Wnt signaling in vivo (Xenopus embryo and mouse hyaloids vessel system).
CAS Number:
294891-81-9 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...