FH535 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulphonamide2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide

BML-WN112-0005 BML-WN112-0025
76002-424EA 75.58 USD
76002-424 76002-426
FH535 ≥98% (by TLC)
FH535

Inhibits the recruitment of the co-activators β-catenin and GRIP1


Antagonizes Wnt/β-catenin/Tcf-mediated transcription as well as PPARγ and δ activity. Able to inhibit the recruitment of the co-activators β-catenin and GRIP1, both of which are activators for both pathways. FH535 was toxic (LC50=5 to 15µM) to 10 of 12 carcinoma cell lines tested. A unique tool to study the relationship between Wnt and PPAR signaling pathways.

Formula: C₁₃H₁₀Cl₂N₂O₄S
MW: 361,2 g/mol
MDL Number: MFCD01212888
CAS Number: 108409-83-2
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