ZnAF-2F ≥95% (by HPCE)

Supplier: ADIPOGEN CORP MS

Synonyms: 6-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2′,7′-difluorofluorescein

CDX-Z0010-M001 CDX-Z0010-M025 CDX-Z0010-M005
102991-246EA 738 USD
102991-246 102991-248 102991-244
ZnAF-2F ≥95% (by HPCE)
ZnAF-2F

ZnAF-1F and ZnAF-2F do not fluoresce in the presence of other biologically important cations such as Ca2+ and Mg2+, and are insensitive to change of pH. The complexes with Zn2+ of previously developed ZnAFs, ZnAF-1, and ZnAF-2 decrease in fluorescence intensity below pH 7.0 owing to protonation of the phenolic hydroxyl group of fluorescein, whose pKa value is 6.2. On the other hand, the Zn2+ complexes of ZnAF-1F and ZnAF-2F emit stable fluorescence around neutral and slightly acidic conditions because the pKa values are shifted to 4.9 by substitution of electron-withdrawing fluorine at the ortho position of the phenolic hydroxyl group. Spectral data: lambdaex 492nm; lambdaem 517nm in PBS.

Formula: C₃₄H₂₆F₂N₄O₅
MW: 608.59 g/mol
Storage Temperature: Freezer
CAS Number: 443302-09-8

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Specification Test Results

Source/Host Synthetic.
Purity 95% (HPCE)
Appearance/Color Solid.
Solubility Soluble in DMSO.

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