Linagliptin

Supplier: ADIPOGEN CORP MS

Synonyms: (R)-8-(3-Aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

AG-CR1-3618-M010 AG-CR1-3618-M050
102988-788EA 55.38 USD
102988-788 102988-790
Linagliptin
Linagliptin

Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4; DPP IV; CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.

Formula: C₂₅H₂₈N₈O₂
MW: 472.55 g/mol
MDL Number: MFCD14635356
CAS Number: 668270-12-0

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