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cis-Platin

Supplier: ADIPOGEN CORP MS

Synonyms: cis-Diamminedichloroplatinum (II) cis-Diammineplatinum (II) dichloride Platinol

AG-CR1-3590-M250 AG-CR1-3590-M050

102988-682EA 96.92 USD

102988-682 102988-680

cis-Platin

cis-Platin

Potent platinum-based antineoplastic agent. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Nephrotoxic when used in vivo. Potent chemoimmunotherapeutic. Stimulates the immune responses by activating macrophages and other cells of the immune system. Apoptosis inducer via p53-dependent and -independent mechanisms. Induces apoptosis through caspase-3 activation and XIAP expression inhibition. Targets other proteins and enzymes. Non-competitive NHE-1 inhibitor, an archetypal, membrane-bound mechanosensitive sodium-hydrogen ion transporter.

Formula: H₆Cl₂N₂Pt
MW: 300.05 g/mol

MDL Number: MFCD00011623
CAS Number: 15663-27-1
UN: 3288
ADR: 6.1,II

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