Okadaic acid sodium salt, high purity


Synonyms: 9,10-deepithio-9,10-didehydroacanthifolicin sodium saltOA sodium salt

AG-CN2-0062-M001 AG-CN2-0062-C025 AG-CN2-0062-C100
102987-198EA 1700 USD
102987-198 102987-194 102987-196
Okadaic acid sodium salt, high purity
Okadaic acid sodium salt

Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0.2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by phosphorylation. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Mimics the effects of insulin. Activates atypical protein kinase C (zeta/lambda) in 3T3/L1 adipocytes. Enhances transmitter release at neuromuscular junctions. Apoptosis inhibitor. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells. Neurotoxic. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling. Stimulates cell motility, loss of stabilization of focal adhesions and a consequent loss of cytoskeletal organization.

Formula: C₄₄H₆₇NaO₁₃
MW: 827.00 g/mol
MDL Number: MFCD00210208
CAS Number: 209266-80-8

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR