cis-Platin ≥98% (by HPLC), Calbiochem®

Supplier: MilliporeSigma
Danger

Synonyms: cis-Diaminodichloroplatinum(II)cis-Diamminedichloroplatinum (II)cis-Diamineplatinum(II) dichloridePlatinolcis-Dichlorodiammine platinum(II)Cisplatin

232120-50MG
80501-024EA 184.53 USD
80501-024
cis-Platin ≥98% (by HPLC), Calbiochem®
cis-Platin

A platinum coordination complex with potent antineoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation.


It is highly soluble in DMSO, Cisplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Sodium chloride solution in water (154 mM NaCl with or without 10 mg/mL mannitol) or PBS (with 140 mM NaCl) is recommended for solubilization prior to culture treatment.

Formula: H₆Cl₂N₂Pt
MW: 300.05 g/mol
Density: 3.738 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00011623
CAS Number: 15663-27-1
EINECS: 239-733-8
UN: 3288
ADR: 6.1,II

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Specification Test Results

Appearance Yellow solid
Purity (by HPLC) ≥98%
Solubility DMSO (10 mg/mL), H₂O with 154 mM NaCl (1 mg/mL), or PBS with 140 mM NaCl (1 mg/mL)
Storage Store at 2 to 8 °C
Stability Unstable in solution; reconstitute just prior to use.

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