Mouse Recombinant Endothelial leukocyte adhesion molecule 1 (ELAM1)

Supplier: Tonbo Biosciences
21-7178-U500 21-7178-U050 21-7178-U100 21-7178-U010
75875-828EA 345.83 USD
75875-828 75875-830 75875-824 75875-826
Mouse Recombinant Endothelial leukocyte adhesion molecule 1 (ELAM1)
E-selectin (CD62E) is a member of the calcium-dependent selectin family. E-selectin, a cell adhesion surface glycoprotein, is also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2). E-selectin is expressed on cytokine activated endothelial cells playing a critical role in inflammation. E-selectin recognizes and binds to sialylated carbohydrates present on the surface proteins expressed by neutrophils, monocytes, eosinophils, memory-effector T-like lymphocytes, and natural killer cells. Macrophage release of cytokines induces the over-expression of E-selectin on endothelial cells of nearby blood vessels. Along with other selectins, E-selectin recruits circulating leukocytes to the site of inflammation. E-selectin is associated with metastatic dissemination of tumor cells by facilitating their escape from the location of the primary tumor. Recombinant Human E-selectin comprises the extracellular signaling domain of the E-selectin protein.
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR