Anti-CD104 Rat Monoclonal Antibody [clone: 346-11A]

Supplier: Southern Biotechnology
100243-962EA 313.85 USD
Anti-CD104 Rat Monoclonal Antibody [clone: 346-11A]
CD104 represents the integrin β4 subunit that associates non-covalently with integrin α6 (CD49f) to form the α6β4 integrin heterodimer. The α6β4 complex is expressed on the basal surface of a variety of epithelial cell types particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes. It also has been found to be associated with a number of malignant tissues. Hemidesmosomal α6β4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments. It is not known if the monoclonal antibody 346-11A can block this adhesion.

Type: Primary
Antigen: CD104
Clonality: Monoclonal
Clone: 346-11A
Conjugation: Unconjugated
Host: Rat
Isotype: IgG2a
Reactivity: Mouse
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