Anti-CD152 Hamster Monoclonal Antibody [clone: 9H10]

Supplier: Southern Biotechnology
100243-788EA 353.08 USD
Anti-CD152 Hamster Monoclonal Antibody [clone: 9H10]
CD152, also known as CTLA-4, is homologous to the costimulatory molecule CD28. Like CD28, the CD152 molecule binds the family of B7 counter-receptors (CD80 and CD86) on antigen-presenting cells. CTLA-4 is not expressed on resting T lymphocytes but is induced 2-3 days following T cell stimulation via the T cell receptor (TCR) complex. Whereas CD28 provides a positive costimulatory signal, CD152 is a negative regulator of T-cell activation, possibly by inhibiting tyrosine kinase signaling through the TCR through its association with tyrosine phosphatases such as SHP-2.

Type: Primary
Antigen: CD152
Clonality: Monoclonal
Clone: 9H10
Host: Hamster
Isotype: IgG
Reactivity: Mouse
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR