Anti-CD3 epsilon Rat Monoclonal Antibody (Biotin) [clone: C363.29B]

Supplier: Southern Biotechnology
100243-098EA 299.46 USD
Anti-CD3 epsilon Rat Monoclonal Antibody (Biotin) [clone: C363.29B]
CD3ε, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa ε chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.

Type: Primary
Antigen: CD3epsilon
Clonality: Monoclonal
Clone: C363.29B
Conjugation: Biotin
Host: Rat
Isotype: IgG2b
Reactivity: Mouse
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