The mass spectrometry-compatible human protein extracts are designed for monitoring mass spectrometry instrument performance. The extracts are predigested and cleaned up by solid-phase extraction for immediate use in liquid chromatography/mass spectrometry (LC-MS) analysis.
- Extract reproducibility is assured by stringent control over the manufacturing process
- Each protein extract is monitored by LC-MS to confirm composition and protein integrity
- To be used as test material for optimizing mass spec protein sample preparation
Lot-to-lot consistency of extracts is monitored by various protein and peptide qualitative and quantitative methods, including LC-MS and amino acid analysis. Our manufacturing process assures compatibility with LC-MS by monitoring non-specific protein fragmentation, non-biological post-translational modifications and, for digested extracts, minimal undigested peptides.