RNase ONE™ Ribonuclease

Supplier: Promega

M4261 M4265

PAM4261EA 144.88 USD

PAM4261 PAM4265

RNase ONE™ Ribonuclease

Enzymes

Single-strand-specific RNA endonuclease. Cleaves between all ribonucleotides.

For sequencing and mapping
Degrades RNA to Cyclic Nucleotide Monophosphate (NMP) Intermediates
Ability to cleave a phosphodiester bond between any two ribonucleotides
Supplied at a concentration of 5-10u/microl

RNase ONE Ribonuclease is a 27kDa periplasmic enzyme from E. coli that catalyzes the degradation of RNA to cyclic nucleotide monophosphate (NMP) intermediates. Slower hydrolysis further catalyzes the degradation of these intermediates to 3'-NMPs. RNase ONE Ribonuclease is one of the few known RNases that can cleave a phosphodiester bond between any two ribonucleotides. RNase ONE Ribonuclease may be used to remove RNA from DNA preparations, for RNase protection assays and for mapping or quantitation of RNA by selective cleavage of single-stranded regions.

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