PTC-124 ≥98% (by HPLC)
Synonyms:
Ataluren
, 3-(5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid
9421-10
9421-50
75837-874EA
99.24
USD
75837-874
75837-876
PTC-124 ≥98% (by HPLC)
PTC-124
PTC-124 has been reported to help the ribosome skip over the premature stop, restore production of functional protein, and thereby potentially treat these genetic diseases.
- Restore cystic fibrosis transmembrane conductance regulator (CFTR) protein expression and function
- Treat genetic diseases
- Helps ribosome skip over premature stop
In a mouse model of cystic fibrosis caused by nonsense mutations, PTC-124 treatment has been shown to restore cystic fibrosis transmembrane conductance regulator (CFTR) protein expression and function.
Formula:
C₁₅H₉FN₂O₃ MW: 284.24 g/mol |
MDL Number:
MFCD09864996 CAS Number: 775304-57-9 |
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