BIOV9649

9649-10 9649-50
75837-782EA 118.45 USD
75837-782 75837-784
BIOV9649
PU-H71 is a potent Heat Shock Protein 90 (Hsp90) inhibitor (IC₅₀ = 50 nM).

Also inhibits cell growth in a range of breast cancer cell lines (IC₅₀ values are 17, 31, 65, 87 and 140 nM for SKBr3, MCF-7, MDA-MB-468, HCC-1806 and MDA-MB-231 cells respectively). Shown to inhibit cell proliferation and induce apoptosis in triple-negative breast cancer (TNBC) cells.
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