KC7F2

Synonyms: N,N'-(Disulphanediylbis(ethane-2,1-diyl))bis(2,5-dichlorobenzenesulphonamide)N,N'-(Disulfanediylbis(ethane-2,1-diyl))bis(2,5-dichlorobenzenesulfonamide)

9641-10 9641-50
75837-764EA 110.91 USD
75837-764 75837-766
KC7F2
KC7F2

KC7F2 is a small molecule HIF-1 pathway inhibitor that inhibits HIF-1α protein translation, but not transcription.


It inhibits hypoxia-induced expression of several HIF target genes, such as carbonic anhydrase IX, matrix metalloproteinase 2, enolase 1, and endothelin 1. KC7F2 is cytotoxic to a variety of cancer cell lines with an IC₅₀ value of 15-25 µM.

Formula: C₁₆H₁₆Cl₄N₂O₄S₄
MW: 570.38 g/mol
MDL Number: MFCD22683809
CAS Number: 927822-86-4
UN: 3316

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