BMS-299897

9606-5 9606-25
75837-496EA 671.3 USD
75837-496 75837-494
BMS-299897
BMS-299897

BMS-299897 is a potent, brain-permeant γ-secretase inhibitor (IC₅₀ = 12 nM).


Inhibits Aβ40 and Aβ42 formation in vitro (IC₅₀ values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo.


Displays no Notch toxicity.

Formula: C₂₄H₂₁ClF₃NO₄S
MW: 511.94 g/mol
MDL Number: MFCD12963627
CAS Number: 290315-45-6
UN: 3316

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR