UNC0379

Synonyms: 6,7-Dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

9588-5 9588-25
75837-472EA 577.91 USD
75837-472 75837-470
UNC0379
UNC0379

UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SET8 (IC₅₀ = 7.3 µM; Kd = 18.3 µM).


It is selective for SET8 over 15 other methyltransferases, including G9a and GLP (IC₅₀s = >100 µM).

Formula: C₂₃H₃₅N₅O₂
MW: 413.56 g/mol
MDL Number: MFCD28167817
CAS Number: 1620401-82-2
UN: 3316

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