Ku-60019

9572-25 9572-5
75837-728EA 437.81 USD
75837-728 75837-726
Ku-60019
Ku-60019

Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC₅₀ = 6.3 nM), blocking the phosphorylation of ATM substrate proteins.


It is much less effective against a panel of 229 other kinases. Ku-60019 sensitizes glioma cells to radiation and inhibits migration and invasion of glioma cells in vitro.

Formula: C₃₀H₃₃N₃O₅S
MW: 547.67 g/mol
MDL Number: MFCD18384974
CAS Number: 925701-49-1
UN: 3316

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