Ku-60019
9572-25
9572-5
75837-728EA
437.81
USD
75837-728
75837-726
Ku-60019
Ku-60019
Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC₅₀ = 6.3 nM), blocking the phosphorylation of ATM substrate proteins.
It is much less effective against a panel of 229 other kinases. Ku-60019 sensitizes glioma cells to radiation and inhibits migration and invasion of glioma cells in vitro.
Formula:
C₃₀H₃₃N₃O₅S MW: 547.67 g/mol |
MDL Number:
MFCD18384974 CAS Number: 925701-49-1 UN: 3316 |
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