LY-2874455
Supplier: BioVision
LY-2874455 is a potent, FGF/FGFR inhibitor.
Exhibits potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship. It displays a 6- to 9-fold in vitro and in vivo selectivity on inhibition of FGF- over VEGF-mediated target signaling in mice..
Formula:
C₂₁H₁₉Cl₂N₅O₂ MW: 444.32 g/mol |
MDL Number:
MFCD22124884 CAS Number: 1254473-64-7 UN: 3316 |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...