Supplier: BioVision

AB216313-25 AB216313-5MG
75837-116EA 454.38 USD
75837-116 75837-118

LY-2874455 is a potent, FGF/FGFR inhibitor.

Exhibits potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship. It displays a 6- to 9-fold in vitro and in vivo selectivity on inhibition of FGF- over VEGF-mediated target signaling in mice..

Formula: C₂₁H₁₉Cl₂N₅O₂
MW: 444.32 g/mol
MDL Number: MFCD22124884
CAS Number: 1254473-64-7
UN: 3316

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