BAY 41-2272

Synonyms: 5-Cyclopropyl-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-amine

9429-5 9429-25
75837-608EA 577.91 USD
75837-608 75837-606
BAY 41-2272
BAY 41-2272

BAY 41-2272 is a soluble guanylyl cyclase (sGC) activator; acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit.


Inhibits platelet aggregation (IC₅₀ = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC₅₀ = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.

Formula: C₂₀H₁₇FN₆
MW: 360.3876 g/mol
MDL Number: MFCD06411391
CAS Number: 256376-24-6
UN: 3316

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR