Human Recombinant G-CSF (from E. coli)

Supplier: Shenandoah Biotechnology
100-72AF-2UG 100-72AF-1MG 100-72AF-10UG 100-72AF-100UG 100-72AF-500UG
10821-670EA 8056.42 USD
10821-670 10821-664 10821-666 10821-996 10821-668
Human Recombinant G-CSF (from E. coli)
Proteins and Peptides
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNFα), interleukin 1 (IL-1), or interleukin 17 (IL-17). The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
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